HPLC Column, RP C4 Butyl, 10um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. Classified as USP L26, this stationary phase provides moderate hydrophobic retention and is well suited for compounds that may be overly retained on more hydrophobic phases such as C8 or C18 columns. The C4 chemistry is commonly used for hydrophobic and neutral compounds, offering efficient separations with reduced retention compared to longer alkyl-chain stationary phases.
68004-05P is a 50 mm x 4.6 mm ID analytical HPLC column packed with 10 µm RP C4 Butyl particles with a 100 Å pore size. The short 50 mm length is optimized for rapid analyses, screening studies, and method development applications where speed is important. The larger 10 µm particle size allows operation at higher flow rates while generating lower backpressure than smaller particle columns, making it particularly useful for method scouting and preparative method development. The 4.6 mm ID format is the industry standard for conventional HPLC systems and typically operates at approximately 1.0–2.0 mL/min.
This USP L26 column is particularly useful for short analyses of hydrophobic and neutral compounds, as well as applications requiring less retention than a C8 column. The combination of fully endcapped C4 chemistry, high-purity silica, and larger 10 µm particles provides robust chromatographic performance for analytical and preparative method development workflows.
Key Benefits
RP C4 Butyl stationary phase
USP L26 classification
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
High-purity silica support
10 µm particles for lower backpressure
Suitable for higher flow rates
Less retention than C8 columns
Excellent for preparative method scouting
Typical Applications
Reversed-phase HPLC
USP L26 methods
Hydrophobic compound analysis
Neutral compound analysis
Rapid analytical methods
Method development
Preparative method scouting
Screening studies
Higher flow rate applications
Specifications
Product Type: HPLC Column
Stationary Phase: RP C4 Butyl
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 50 mm
Length: 50 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Brand: Cogent
Important Notes
Designed for reversed-phase chromatography
Provides less retention than comparable C8 columns
Suitable for hydrophobic and neutral compounds
Larger particle size reduces operating backpressure
Well suited for preparative method development
Compatible with conventional HPLC systems
Alternative for many USP L26 methods